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The Neuro Defence System
The Neuro Defence System
AM/PM - Sleep, Focus & Protection
BUNDLE PRICE STARTS AT
$112.00 SGD
The Neuro Defence System combines The Brain for AM clarity and cognitive performance with The Unwind for PM calm and overnight brain restoration — supporting focus by day, recovery by night, and long-term brain protection.
Sharpens focus and mental clarity
Calms the mind and supports deep sleep
Protects long-term cognition
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Complete Your Routine
The Repair – NMN+
$59.00 SGD
+
The Age Defence System
$150.00 SGD
$177.00 SGD
+
100,000+ Products Sold
Science Backed
No toxins
Vegan-friendly
Allergen-free
Gluten-free
No heavy metals
3rd-Party Tested
90-Day Money Back Guarantee
How it works
How it works
Stay sharp by day. Restore by night. The Neuro Defence System is a complete day-and-night brain support system designed to sharpen focus, build stress resilience, and support deep, restorative sleep — protecting cognitive health now and long term.
By pairing an advanced nootropic formula with a clinically studied brain calm and sleep complex, it supports daily performance while enhancing overnight brain repair and recovery.
Daily benefits:
- Sharper focus, clarity, and memory
- Improved stress resilience and mood balance
- Reduced mental fatigue
- Deeper, more restorative sleep
- Overnight brain recovery
- Healthier brain ageing
How it works:
By day, Rhodiola rosea supports stress resilience and sustained performance, Ginkgo biloba 24/6 enhances cerebral blood flow for focus and memory, and ErgoX™ Ergothioneine helps protect neurons from oxidative stress.
By night, Magtein® magnesium L-threonate — the only magnesium proven to cross the blood–brain barrier — supports sleep regulation, while L-theanine promotes calm, relaxed brain activity for deeper sleep.
What's in the bundle
What's in the bundle
The Neuro Defence System is designed by Dr Jan Gruber and Dr Vincenzo Sorrentino, professors at the National University of Singapore (NUS).
Serving Size:
Day: 1 capsule (The Brain)
Night: 2 capsules (The Unwind)
Servings Per System: 30 (1 month supply)
Active Ingredients:
- Rhodiola rosea extract 3%, 200mg
- Ginkgo biloba extract 24/6, 120mg
- ErgoX™ Ergothioneine, 25mg
- Magtein® Magnesium L-Threonate, 1000mg (72mg elemental magnesium)
- L-Theanine, 250mg
Origin: Made in France (The Brain) and the US (The Unwind)
Standardisation & Purity: Ginkgo 24/6 is the gold-standard extract used in most clinical trials. ErgoX™ Ergothioneine is ≥99.5% pure and produced to cGMP/ISO standards. Magtein® is clinically studied for brain magnesium delivery.
How to use
How to use
How to take:
Take 1 capsule of The Brain daily with a glass of water, preferably in the morning or early afternoon.
Take 2–4 capsules of The Unwind in the late afternoon or evening to support relaxation, sleep quality, and overnight brain recovery.
Expiry dates & Lab test reports
Expiry dates & Lab test reports
Triple-tested by independent labs. Unlike most brands.
We screen every batch for purity, safety, and potency — so you know exactly what’s in every capsule.
We typically ship the latest batches, each with an expiry date at least 1–2 years ahead, ensuring lasting freshness and stability.
Shipping
Shipping
Experience fast shipping to many countries worldwide.
🇸🇬 Singapore
- Free shipping on all orders
- Delivery time: 1-2 business days
🇦🇺 Australia
- Cost: Free for orders over $100 AUD, or $10 AUD for smaller orders
- Delivery time: 2-3 business days
🇲🇾 Malaysia
- Free shipping on all orders
- Delivery time: 3-4 business days
🇺🇸 United States
- Cost: Free for orders over $75 USD, or $10 USD for smaller orders
- Delivery time: 3-4 business days
🇨🇦 Canada
- Cost: Free for orders over $100 CAD, or $15 CAD for smaller orders
- Delivery time: 3-4 business days
🇭🇰 Hong Kong SAR
- Cost: Free for orders over $600 HKD, or $60 HKD for smaller orders
- Delivery time: 1-2 business days
🇦🇪 United Arab Emrirates
- Cost: Free for orders over 300 AED, or 30 AED for smaller orders
- Delivery time: 2-3 business days
Or for rest of the world:
Take our quiz
Take our quiz
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Scientist's Tips
Scientist's Tips
“Brain health isn’t built by a single supplement — it’s shaped by what you do during the day and how well your brain recovers at night. The Neuro Defence System supports focus and stress resilience by day, while promoting calm, deep sleep and overnight brain repair.”
— Dr Jan Gruber, NUS Professor & For Youth Scientific Advisor
AM / PM Brain Defence
Daytime clarity. Night-time restoration. Long-term cognitive protection.
#1
The only magnesium proven to cross the blood–brain barrier⁽¹⁾
2×
Improved deep sleep scores vs placebo in 2 weeks⁽²⁾
4.8×
Greater mood improvement vs placebo in 3 weeks⁽²⁾
2.5×
Memory improvement at 4 weeks⁽³⁾
Our products are formulated by Dr Jan Gruber and Dr Vincenzo Sorrentino, professors at the National University of Singapore (NUS). ⁽¹⁾ Slutsky I. et al., 2010, Neuron ⁽²⁾ Hausenblas H.A. et al., 2024, Sleep Medicine ⁽³⁾ Zajac I.T. et al., 2025, Nutraceuticals
Trusted by 10,000s of customers.
What to Expect Over 12 Weeks.
Experience real, noticeable change—backed by science and felt in your body.
Try our products risk-free for 90 days.
If you're not satisfied, just tell us about your experience.
IN JUST 1-2 WEEKS:
Calmer mood, reduced daily stress, and a more relaxed pre-sleep routine
Noticeable boost in focus and mental clarity during the day
IN 4-6 WEEKS:
Deeper, higher-quality sleep with improved next-day energy
Improved memory, performance, and resilience under stress
AFTER 10-12 WEEKS
Sustained cognitive vitality and steadier mood in demanding situations
Long-term neuroprotection supporting healthy brain ageing
Deep Sleep, Restored Mind
Sleep deeper, wake sharper, feel calm.
Clarity Today, Sharper Tomorrow.
Support memory, protect neurons, and strengthen cognitive resilience — today’s clarity layered with tomorrow’s brain protection.
Why Choose The Neuro Defence System?
Others
Day + night brain support system
Clinically studied, patented ingredients
Gold-standard Ginkgo 24/6 & Magtein® magnesium
Lab test certificates published online
Made in France and the US under GMP
High Standards. No Compromises.
Every ingredient is tested, verified, and obsessively sourced—because good enough isn’t good enough.
Ingredients in The Unwind
Magtein® Magnesium L-Threonate, L-Theanine
Ingredients in The Unwind
Magtein® magnesium L-threonate uniquely crosses the blood–brain barrier to support sleep, relaxation, and brain health. Paired with L-theanine, a tea-derived amino acid that boosts calming alpha brain waves, it reduces stress and promotes relaxed focus — without drowsiness or energy crashes.
Ingredients in The Brain
ErgoX™ Ergothioneine, Ginkgo Biloba 24/6, Rhodiola Rosea 3%
Ingredients in The Brain
ErgoX™ Ergothioneine is a pure antioxidant amino acid that accumulates in the brain to support long-term cognitive protection. Combined with gold-standard Ginkgo biloba 24/6 for blood flow and clarity, and Rhodiola rosea for stress resilience, it supports sharper focus and sustained mental performance.
Meet Our Scientists.
Jan Gruber
PhD
University of Oxford, UK
Dr. Jan Gruber, PhD, is a biochemist and Associate Professor at the National University of Singapore (NUS), specialising in ageing biology, mitochondrial function, and oxidative stress. His research explores the molecular mechanisms of longevity and has been published in leading journals. He completed his PhD in Biochemistry at the University of Oxford and also studied physics and mathematics at the University of Cambridge. His work often uses simple organisms such as tiny worms (C. elegans) to understand how ageing happens at the cellular level, and to test new ways to slow it down.
Vincenzo Sorrentino
PhD
University of Amsterdam, NL
Dr. Vincenzo Sorrentino, PhD, is a molecular biologist and Assistant Professor at the National University of Singapore (NUS), specialising in ageing, mitochondrial health, and NAD⁺ metabolism. His research has been published in leading journals including Nature and Cell Reports. He completed his PhD in Medical Biochemistry at the University of Amsterdam and went on to study how metabolism and nutrition affect ageing. His current work looks at how molecules like NAD⁺, which fuel our cells, and the maintenance of proteins in the body, can support healthier ageing.
Ask Anything.
What is The Neuro Defence System?
The Neuro Defence System is a complete day-and-night brain support system combining The Brain (daytime focus and resilience) and The Unwind (night-time calm and sleep support). Together, they support cognitive performance, stress resilience, sleep quality, and long-term brain health.
How should I take The Neuro Defence System?
Day: Take 1 capsule of The Brain in the morning or early afternoon. Night: Take 2–4 capsules of The Unwind in the late afternoon or evening, ideally about one hour before bed.
How quickly will I notice results?
Many people notice improved focus, calmer mood, or better sleep within 1–2 weeks, if not days. Deeper benefits — such as steadier energy, improved resilience, and long-term cognitive support — build with consistent daily use over 4–6 weeks.
Is The Neuro Defence System safe?
All ingredients are well-researched, clinically studied, and triple-tested for purity. However: Do not use if pregnant or breastfeeding. Consult your healthcare provider before use if you have a medical condition or take medications — especially antidepressants, blood thinners, sedatives, or blood pressure medication. Ginkgo biloba may increase bleeding risk in some individuals. Discontinue use if adverse effects occur.
Who is The Neuro Defence System for?
Adults who want: Sharper focus and mental clarity Better stress resilience Deeper, more restorative sleep Long-term brain protection as they age Especially valuable for those under high cognitive or emotional demand.
Read more in our blog.
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