
NMN vs. NAD+: What’s the Difference?
|
|
Time to read 2 min
|
|
Time to read 2 min
You've heard the hype around NMN and NAD+ , but what's the real story? Are they interchangeable? Should you take both?
This article breaks down the science, the benefits, and the key differences — so you can choose the right supplement for your longevity and energy goals.
NAD+ is a molecule your body needs for energy, DNA repair, and cellular defence.
NMN is a precursor to NAD+ — your body converts NMN into NAD+ internally.
NAD+ itself isn’t easily absorbed when taken orally. NMN is the smarter way to raise NAD+ levels.
Both are key to healthy ageing, but NMN is the more practical supplement .
NAD+ (nicotinamide adenine dinucleotide) is a molecule found in every living cell. It powers:
🔋 Cellular energy production (ATP)
🧬 DNA repair
🧠 Brain function
🛡️ Cell defence and detoxification
⏳ Activation of sirtuins (longevity enzymes)
As you age, NAD+ levels drop by as much as 50% by age 50 — contributing to fatigue, slower metabolism, and increased disease risk.
The problem? NAD+ is too large to absorb effectively in supplement form , which is why scientists look to precursors like NMN and NR instead.
NMN (nicotinamide mononucleotide) is a direct precursor to NAD+. It’s a molecule your body easily absorbs and converts into NAD+ in a few short steps.
It supports:
✔️ Increased NAD+ production
✔️ Better energy metabolism
✔️ Improved brain and heart health
✔️ Anti-ageing and DNA repair
✔️ Muscle performance and endurance
Studies show NMN supplementation can quickly raise NAD+ levels, especially when taken consistently in the morning .
While NAD+ is available as an injectable or IV therapy, oral NAD+ supplements have low bioavailability — meaning very little gets absorbed into your bloodstream.
In contrast, NMN has:
💊 Proven oral absorption
🔬 Clinical studies showing increases in blood NAD+
🧪 Benefits across energy, inflammation, and cognition
So if you want more NAD+, NMN is the smarter way to get there .
250 mg Uthever® NMN
Clean, minimalist formula
Best for first-time users and daily longevity maintenance
Encapsulated in Europe
450 mg NMN + 50 mg apigenin + 50 mg L-tryptophan
Supports NAD+, inflammation, and mood in one capsule
Designed for deeper anti-ageing benefits and recovery
Feature | NAD+ (oral) | NMN |
---|---|---|
Absorption | ❌ Poor | ✅ Excellent |
Direct NAD+ Increase | ✅ Direct (IV/IM only) | ✅ Converts to NAD+ |
Clinical Research | ⚠️ Limited (oral) | ✅ Strong in animals + humans |
Accessibility | ❌ Often expensive | ✅ Easy and affordable |
Practical for Daily Use | ❌ Not ideal | ✅ Ideal |
NAD+ powers your longevity — but NMN is how you get there.
Whether you're starting your anti-ageing journey or levelling up your NAD+ strategy, NMN supplements are the smart, science-backed way to boost your biology.
Choose The Base for simple daily maintenance — or The Repair if you're serious about results.