The Legal Status of NMN in the United States (2025 Update)

In the ever-evolving world of wellness and supplements, NMN (Nicotinamide Mononucleotide) is going through a legal rollercoaster. Hailed as a game-changing anti-ageing molecule, NMN’s legal status in the United States and abroad has seen more twists than a season of political drama.

First sold widely as a longevity supplement, sales were briefly restricted — but never banned due to safety concerns, and enforcement in the US is currently on pause.

Now, a new voice has entered the mix – United States Secretary of Health and Human Services Robert F. Kennedy Jr. – whose views on longevity science could signal hope for NMN’s future.

NMN, short for Nicotinamide Mononucleotide, is a compound that naturally occurs in the body and plays a key role in energy production and cellular repair. It’s a direct precursor to NAD+ (nicotinamide adenine dinucleotide), a coenzyme essential for metabolism, cellular repair and overall healthspan.

As NAD+ levels decline with age, boosting NMN intake has been linked to:

• Energy production

• DNA repair

• Brain function

• Healthy ageing

That’s why it’s become a favourite among biohackers, longevity researchers and everyday health enthusiasts across the world — including in the US, where ageing populations are actively seeking out science-backed supplements.

For years, NMN was sold freely online and in supplement shops. But in a surprise move, the US Food and Drug Administration (FDA) reversed its earlier approval of NMN as a dietary ingredient in late 2022.

The reason? The agency claimed that NMN was under investigation as a drug, which under US law would disqualify it from being marketed as a supplement — unless it was already approved before drug trials began.

Despite widespread concern and misleading headlines, NMN has never been officially banned in the United States by the FDA. Rather, it was excluded from the list of recognised dietary supplements, leading the FDA to attempt to restrict its sale. The full document can be downloaded from the FDA website here. However, in 2024, a US federal court ruled that this action was unlawful, providing clarity and renewed confidence for both consumers and the supplement industry.

The timeline around those drug investigations remains unclear. The FDA doesn't publicly disclose when drug studies start, so NMN suppliers were essentially caught off guard. The trouble is, the legal timeline remains murky. The FDA does not disclose when a drug investigation begins, which has left supplement brands in limbo.

• The US FDA "ban" for NMN was not related to safety

• NMN continues to have a strong track record for purity and tolerability

• The ruling ultimately came down to a regulatory technicality

The Natural Products Association (NPA) has been leading the charge against the FDA’s "ban". Its president, Dr. Daniel Fabricant, called the FDA’s action an “overreach” and encouraged supplement makers to keep NMN on the shelves, arguing that the decision does not yet represent a final ruling.

In 2024, the NPA scored a major legal victory that gave fresh momentum to NMN advocates. While details are still emerging, the win shows that the fight is far from over, and it strengthens the argument that NMN deserves clear, science-based regulation – not bureaucratic stonewalling.

The Natural Products Association (NPA) challenged the ruling:

• March 2023 : NPA filed a formal petition with the FDA

• August 2023 : NPA launched a lawsuit against the agency

• November 2024 : A US federal court ruled in favour of the NPA, stopping the FDA from taking action against NMN products while the case is on hold.

What does the ruling against the US FDA mean?

• NMN supplements can still be legally sold in the U.S.

• The FDA cannot currently enforce its attempted restriction

• The legal status of NMN is still under review — but it's not banned

Our commitment to quality begins at the source and continues through every step of production. Each batch of NMN is independently lab-tested to ensure purity, potency, and safety. Our formulations are developed by leading experts in longevity science, combining cutting-edge research with real-world results.

We formulate all products in Singapore, manufacture and test our NMN in Europe under stringent standards for quality assurance before being shipped to customers around the world. Our NMN lineup includes:

The Base – NMN

• 250 mg of 99% pure NMN, ideal for daily NAD+ support and cellular energy.

The Repair – NMN+

• A powerful blend of 450 mg pure NMN with apigenin and pterostilbene, designed to support cellular repair, metabolic health, and healthy aging.

Whether you’re a biohacker, a wellness consumer, or someone curious about healthy ageing, NMN’s journey is worth watching. Legal victories, political shifts, and growing consumer demand all point to one truth – the fight for longevity isn’t just scientific. It’s political, legal and deeply personal.

For now, stay informed, read your labels, and follow trusted updates. The NMN story is far from over.