Bryan Johnson’s Blueprint & Supplements Simplified
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Time to read 18 min
How to Hack Ageing Without a Million-Dollar Lab
Bryan Johnson has become famous for spending millions each year attempting to slow his biological ageing. His Blueprint protocol involves doctors, constant blood testing, strict routines and an extensive supplement stack.
It is fascinating. It is data driven. It is also unrealistic for most people.
The real question is this: how much of Blueprint’s benefit comes from expensive optimisation, and how much comes from fundamentals that are already backed by decades of science?
When you strip it down, most of the measurable gains come from four pillars:
Sleep. Nutrition. Exercise. Social connection.
The good news is that these pillars are accessible. You do not need a laboratory to apply them.
The Goal and Principles of Project Blueprint
The Blueprint protocol is a comprehensive health regimen aimed at slowing and reversing biological ageing through extreme diet, exercise, sleep, and a vast array of supplements and treatments. As Bryan Johnson tries different approaches and treatments and measures his biomarkers, the protocol evolves to ensure he gets maximum value from every aspect.
Table of contents
Bryan Johnson’s Blueprint Supplements Starter Guide Simplified (February 2026 Update) 1. Essential Capsules 2. Longevity Mix 3. Advanced Antioxidants 4. NAC + Ginger + Curcumin Which longevity supplement system is more comprehensive? Price comparison Blueprint supplements For Youth supplements Why the For Youth option can be more budget-friendly From Bryan Johnson’s Blueprint to Your Daily Routine Key Takeaways Want help choosing the right longevity supplements? Scientific References
Bryan Johnson’s Blueprint Supplements Starter Guide Simplified (February 2026 Update)
Bryan Johnson’s Blueprint protocol includes a range of supplements designed to support longevity, metabolic health, and overall wellbeing. These products aim to simplify the complex supplement routine Johnson personally follows by packaging key nutrients and compounds into a smaller number of formulas. The supplements are typically taken daily as part of a structured routine that combines diet, exercise, and sleep optimisation.
Below is an overview of several of the core supplements in the Blueprint range, including their ingredients, recommended consumption methods, and intended benefits.
1. Essential Capsules
Essential Capsules are designed as the foundational supplement within the Blueprint stack. Instead of taking many separate vitamin and mineral supplements, this product provides a broad spectrum of micronutrients in one capsule formula.
The goal of this supplement is to ensure that the body receives key nutrients needed for metabolism, cellular health, and general physiological function, particularly for individuals who want a simplified daily supplement routine.
Active Ingredient list
Ingredient |
Amount Per Serving |
% Daily Value |
Vitamin D (as Cholecalciferol) |
50 mcg (2000 IU) |
250% |
Vitamin E (d-alpha-Tocopherol) |
67 mg |
447% |
Thiamin (Vitamin B1) (as HCl) |
1.1 mg |
92% |
Riboflavin (Vitamin B2) |
1.4 mg |
108% |
Niacin (as Niacinamide) |
15 mg |
94% |
Vitamin B6 (as Pyridoxine HCl) |
1.4 mg |
82% |
Folate (as Calcium L-5-Methyltetrahydrofolate) |
200 mcg DFE |
50% |
Vitamin B12 (as Methylcobalamin) |
125 mcg |
5208% |
Biotin |
50 mcg |
167% |
Pantothenic Acid (as D-Calcium Pantothenate) |
6 mg |
120% |
Calcium (from Dicalcium Phosphate) |
50 mg |
4% |
Iodine (as Potassium Iodide) |
200 mcg |
133% |
Zinc (as Bisglycinate) |
15 mg |
136% |
Selenium (as L-Selenomethionine) |
28 mcg |
51% |
Manganese (as Citrate) |
1 mg |
43% |
Nicotinamide Riboside (as Chloride) |
300 mg |
† |
Broccoli Seed Extract (Glucoraphanin 20 mg) |
200 mg |
† |
Fisetin (from Stem of Smoketree Extract) |
100 mg |
† |
Luteolin (from Bud of S. japonica Extract) |
100 mg |
† |
Ubiquinol (as Reduced CoQ10) |
50 mg |
† |
Lactobacillus acidophilus (4 Billion CFU) |
20 mg |
† |
Spermidine (as Trihydrochloride) |
10 mg |
† |
Boron (as Glycinate) |
3 mg |
† |
Lithium (as Orotate) |
1 mg |
† |
† Daily Value not established
(Source: https://blueprint.bryanjohnson.com/products/essentials-capsules)
Benefits
This supplement is intended to provide comprehensive micronutrient support. Vitamins and minerals help maintain immune function, metabolic processes, and bone health, while compounds such as CoQ10 support cellular energy production. The inclusion of plant polyphenols and probiotic strains may also contribute to gut health and cellular protection.
Essential Capsules contain a broad mix of vitamins, minerals, and polyphenols designed to cover multiple nutritional bases. However, for individuals without specific deficiencies, many of these micronutrients can already be obtained through a balanced diet rich in vegetables, fruits, and whole foods.
💡 For Youth RecommendationThe Age Defence System combines three coordinated formulations designed to repair, protect, and cleanse cells at the same time.
Active ingredientsThe Repair – NMN+
The Protect – Glutathione+
The Cleanse – Spermidine+
BenefitsThe Age Defence System takes a three-step approach to longevity. NMN helps raise NAD⁺ levels [1], a key molecule required for cellular energy production and repair. Apigenin and pterostilbene help sustain NAD⁺ activity and support mitochondrial efficiency, allowing cells to maintain energy and resilience as they age. [2] [3] What distinguishes this formulation is the use of clinically studied, highly bioavailable ingredient forms. For example, both Meriva® Curcumin Phytosome™ and Quercefit® Quercetin Phytosome™ use phospholipid delivery systems that significantly improve the body’s ability to absorb plant compounds. [4] Curcumin is naturally difficult to absorb, but phytosome formulations such as Meriva have been shown in human studies to produce around 29-fold higher absorption compared with standard curcumin extracts. [5] Similarly, quercetin phytosome formulations have demonstrated substantially improved bioavailability compared with unformulated quercetin, enabling higher plasma levels and more effective utilisation in the body. [6] This matters because many plant compounds associated with longevity research have low natural absorption, meaning a large portion of the dose may pass through the body unused if not delivered using advanced formulations. In addition, the Age Defence System uses traceable branded ingredients such as Uthever™ NMN, Setria® glutathione, Meriva® curcumin, and Quercefit® quercetin. These ingredients are produced under controlled manufacturing processes and are widely used in clinical research, which improves consistency and transparency compared with generic extracts. Finally, spermidine, curcumin, and quercetin support autophagy, the body’s natural cellular clean-up process that removes damaged components and helps maintain healthier cells over time. [7] [8] [9] By combining NAD⁺ restoration, antioxidant protection, and cellular renewal in one coordinated system, the formulation targets several of the biological mechanisms linked to ageing rather than focusing on a single pathway. While Blueprint supplements and The Age Defence System are not directly one-to-one equivalents, the use of high-bioavailability delivery systems, traceable branded ingredients, and a coordinated three-pillar longevity strategy allows the formulation to deliver similar goals through ingredients that are designed to be absorbed more efficiently and used more effectively by the body. |
2. Longevity Mix
Longevity Mix is one of the flagship supplements in the Blueprint product line. It is a powdered drink designed to combine several amino acids, antioxidants, and metabolic support compounds into a single daily serving. The idea behind the formula is to reduce the need for multiple individual supplements while still providing nutrients that may support energy metabolism, cellular repair, and stress management.
Active Ingredient list
Ingredient |
Amount Per Serving |
% Daily Value |
Calories |
10 |
|
Total Carbohydrates |
3 g |
1%** |
Vitamin C (as Ascorbic Acid) |
250 mg |
278% |
Calcium (from CaAKG) |
400 mg |
31% |
Magnesium (as Mag Citrate) |
150 mg |
36% |
Creatine (as Monohydrate) |
2500 mg |
† |
Calcium Alpha-Keto Glutarate |
2000 mg |
† |
Taurine |
1500 mg |
† |
Glycine |
1200 mg |
† |
L-Lysine (as HCl) |
1000 mg |
† |
Glucosamine Sulfate (as KCl) |
750 mg |
† |
L-Glutathione (Reduced) |
250 mg |
† |
L-Theanine |
200 mg |
† |
Sodium Hyaluronate |
120 mg |
† |
* Percent Daily Values are based on a 2,000 calorie diet.
† Daily Value not established.
(Source: https://blueprint.bryanjohnson.com/products/longevity-blend-multinutrient-drink-mix-blood-orange-flavor)
Benefits
The formula is intended to support several aspects of health associated with longevity. Creatine and amino acids may help with energy production and muscle recovery, while compounds such as L-theanine and ashwagandha are commonly used to support stress regulation and cognitive focus. Antioxidant ingredients like vitamin C and glutathione are included to help protect cells from oxidative stress.
💡 For Youth RecommendationThe Repair – NMN+ is designed to boost cellular energy by increasing NAD⁺ levels.
Active ingredientsThe Repair – NMN+
BenefitsNMN acts as a precursor that the body uses to produce NAD⁺, a coenzyme essential for cellular energy metabolism and mitochondrial function. Because NAD⁺ levels naturally decline with age, restoring NAD⁺ helps support cellular repair, metabolic health, and energy production. Research shows that NMN supplementation can increase NAD⁺ levels in humans, supporting metabolic and cellular health pathways linked to ageing. [1] The Repair strengthens this pathway by combining NMN with apigenin and pterostilbene, creating a more comprehensive approach than NMN alone. Apigenin helps reduce NAD⁺ depletion by inhibiting the CD38 enzyme, which becomes more active with age and accelerates NAD⁺ breakdown. [10] Pterostilbene supports mitochondrial function and metabolic signalling associated with healthy ageing. [2] [11] [12] One advantage of this formulation is the use of traceable, clinically studied ingredients, particularly Uthever™ NMN. Human clinical trials using Uthever NMN have shown significant increases in NAD⁺ levels, with one study reporting up to a 38 percent rise in NAD⁺/NADH levels after 60 days of supplementation. [13] Compared with many NAD⁺ supplements that rely on a single ingredient, this multi-component approach supports several points in the NAD⁺ pathway. While Blueprint supplements may include ingredients related to metabolic health, The Repair specifically targets NAD⁺ restoration, protection, and mitochondrial efficiency in one formula, using standardised ingredients with documented traceability and clinical data. As a result, The Repair aims to deliver more reliable and sustained NAD⁺ support, while maintaining ingredient quality and transparency through branded, research-backed compounds. |
3. Advanced Antioxidants
Advanced Antioxidants is a supplement focused on delivering fat-soluble antioxidant nutrients. These compounds are known for their ability to neutralise free radicals and support cellular health, particularly in tissues exposed to oxidative stress.
Many of the ingredients in this formula belong to a class of compounds called carotenoids, which are naturally found in fruits and vegetables and are associated with eye health, cardiovascular function, and long-term cellular protection.
Active Ingredient list
Ingredient |
Amount Per Serving |
% Daily Value |
Vitamin K1 (as Phytonadione) |
1500 mcg |
1250% |
Lycopene |
15 mg |
† |
Astaxanthin (from Haematococcus pluvialis Microalgae) |
12 mg |
† |
Lutein (from Marigold Flower Extract) |
10 mg |
† |
Vitamin K2 MK4 (as Menaquinone-4) |
5 mg |
† |
Zeaxanthin (from Marigold Flower Extract) |
2 mg |
† |
Vitamin K2 MK7 (as Menaquinone-7) |
600 mcg |
† |
† Daily Value not established.
(Source:https://blueprint.bryanjohnson.com/products/advanced-antioxidants)
Benefits
This supplement is designed to support antioxidant defences in the body. Carotenoids such as lutein and zeaxanthin are associated with eye health, while lycopene and astaxanthin may help support cardiovascular and skin health. Vitamin K forms included in the formula also contribute to normal blood clotting and bone metabolism.
💡 For Youth RecommendationThe Protect – Glutathione+ supports the body’s natural defence systems against oxidative stress.
Active ingredientsThe Protect – Glutathione+
BenefitsGlutathione is one of the body’s most important antioxidants and plays a key role in neutralising free radicals that can damage cells. [14] [15] It also supports detoxification processes in the liver and contributes to immune defence and cellular repair. [16] [17] Sulforaphane complements this by activating the body’s own antioxidant response pathways, particularly the Nrf2 pathway, which helps the body produce its own protective enzymes and strengthen long-term cellular resilience. [18] The Protect combines these two mechanisms in a single formulation, pairing Setria® Glutathione, a clinically studied and traceable form of glutathione, with Sulfodyne® Sulforaphane derived from broccoli seed extract. [19] [20] Using standardised, branded ingredients helps ensure consistent potency and transparency compared with generic antioxidant extracts that may vary in quality. Compared with antioxidant blends that rely on general plant extracts, this formulation targets both direct antioxidant protection and activation of the body’s internal defence systems. While Blueprint supplements provide antioxidant support through carotenoids and fat-soluble vitamins, The Protect focuses specifically on strengthening the body’s core antioxidant and detoxification pathways, offering a more targeted approach to cellular protection, inflammation balance, and immune resilience. |
4. NAC + Ginger + Curcumin
The NAC + Ginger + Curcumin supplement combines three well-known compounds often used for antioxidant and anti-inflammatory support. Each ingredient plays a different role in supporting cellular health and metabolic balance.
NAC is a precursor to glutathione, one of the body’s most important antioxidants. Ginger and curcumin, both derived from plant sources, are widely studied for their potential anti-inflammatory and digestive benefits.
Active Ingredient list
Ingredient |
Amount Per Serving |
% Daily Value |
N-Acetyl-Cysteine |
1200 mg |
† |
Ginger Extract std. 26% Gingerols (as Zingiber officinale Roscoe) |
400 mg |
† |
Curcumin extract std. 85% Curcuminoids (as Curcuma longa) |
250 mg |
† |
† Daily Value not established.
(Source: https://blueprint.bryanjohnson.com/products/nac-ginger-capsules)
Benefits
This formula is intended to support the body’s antioxidant systems and help regulate inflammation. NAC contributes to the production of glutathione, while ginger and curcumin are commonly used to support metabolic health, digestion, and immune function.
💡 For Youth RecommendationThe Cleanse – Spermidine+ supports autophagy and helps remove damaged cellular components.
Active ingredientsThe Cleanse – Spermidine+
BenefitsSpermidine helps activate autophagy, the body’s natural cellular recycling process that removes damaged proteins and dysfunctional components so cells can renew themselves. Autophagy is strongly linked with longevity research, and studies show spermidine can stimulate protective autophagy pathways and support cellular maintenance processes associated with healthy ageing. [21] The Cleanse strengthens this pathway by combining spermidine with curcumin and quercetin, two plant-derived compounds known for their anti-inflammatory and antioxidant effects. Curcumin helps regulate inflammatory signalling and oxidative stress, while quercetin supports immune resilience and cellular defence. [5] [6] [8] One key advantage of this formulation is the use of high-bioavailability phytosome ingredients. Both Meriva® Curcumin Phytosome™ and Quercefit® Quercetin Phytosome™ bind the plant compounds to phospholipids, significantly improving absorption compared with standard extracts. [4] Curcumin in particular is known to have poor natural bioavailability, meaning much of the compound may pass through the body unused without enhanced delivery systems. [22] By contrast, the Blueprint NAC + Ginger + Curcumin formula focuses primarily on antioxidant support and inflammation balance. NAC helps replenish glutathione, one of the body’s most important antioxidants, which plays a role in detoxification and cellular protection. Ginger and curcumin also provide anti-inflammatory and digestive support. However, the mechanisms are different. While NAC-based formulas mainly support antioxidant production, The Cleanse specifically targets cellular renewal and autophagy, an upstream longevity pathway associated with clearing damaged proteins and senescent cells. In addition, the use of phytosome technology and traceable branded ingredients allows The Cleanse to deliver plant compounds in forms designed to be absorbed and utilised more effectively. As a result, The Cleanse offers a more targeted longevity strategy, focusing on autophagy activation and enhanced bioavailability rather than primarily supporting antioxidant production alone. |
Which longevity supplement system is more comprehensive?
Bryan Johnson’s Blueprint supplements reflect an important shift in the longevity supplement industry. Rather than relying on traditional multivitamins, the Blueprint system focuses on compounds that target specific biological pathways linked to ageing, such as mitochondrial function, inflammation regulation, and metabolic health. The approach highlights how modern longevity supplements increasingly focus on mechanisms of ageing rather than simply filling nutritional gaps.
One thing we can learn from Blueprint is the importance of targeted ingredients. Compounds such as creatine, glycine, NAC, and plant polyphenols are commonly studied in metabolic health and longevity research. However, many of these nutrients can also be obtained through a balanced diet rich in whole foods, vegetables, nuts, and protein sources.
Another difference lies in dosage strategy and ingredient amounts. Some Blueprint formulations include nutrients in quantities that significantly exceed daily nutritional requirements. While this approach aims to maximise potential benefits, extremely high doses are not always necessary for long term health if a person already consumes a nutrient dense diet.
The For Youth approach takes a slightly different direction. Instead of focusing primarily on increasing ingredient quantities, the emphasis is on improving how effectively the body can absorb and use those compounds. Many plant compounds associated with longevity research, such as curcumin and quercetin, have naturally low bioavailability when consumed in standard extract form. [22]
This is where phytosome technology becomes important. Phytosomes bind plant compounds to phospholipids, allowing them to pass through cell membranes more efficiently. Human pharmacokinetic studies of curcumin phytosome formulations such as Meriva® have shown substantially higher absorption compared with standard curcumin extracts, with plasma concentrations reported to be up to 29 times higher in some studies. [4] [6]
In practical terms, both systems aim to support similar longevity pathways. Blueprint demonstrates how targeted supplements can support metabolic and cellular health, while For Youth focuses on delivering key compounds in highly absorbable, traceable forms rather than relying on very high doses.
Taken together, the comparison highlights two different philosophies in longevity supplementation. Blueprint emphasises ingredient quantity and stacking multiple supplements, whereas the For Youth system focuses on bioavailability, clinically studied ingredient forms, and efficient delivery, ensuring the body can utilise those compounds more effectively.
Price comparison
When comparing longevity supplement systems, cost can quickly become a major factor because many protocols require multiple products.
Blueprint supplements
Typical Blueprint supplements are sold individually and may require purchasing several products to build a full stack.
Example pricing often seen in listings:
Longevity Mix: approximately S$50 per month
Essential Capsules: approximately S$63 per month
Advanced Antioxidants: approximately S$63 per month
NAC + Ginger + Curcumin: approximately S$35 per month
(Source: https://blueprint.bryanjohnson.com/products/)
This means that building a multi-product stack can significantly increase the overall monthly cost, up to S$211 every month.
For Youth supplements
For Youth offers both individual supplements and bundled systems.
Current pricing include:
The Repair – NMN+: about S$59 per month
The Protect – Glutathione+: about S$59 per month
The Cleanse – Spermidine+: about S$59 per month
However, the full Age Defence System bundle costs around S$150, which combines all three products in a single monthly kit.
Why the For Youth option can be more budget-friendly
While both supplement systems aim to support longevity, the structure of the For Youth system can make it easier to manage from a budget perspective.
1. Bundled longevity stack
The Age Defence System combines three specialised formulations into a single bundle rather than requiring several separate purchases. This simplifies both the routine and the cost.
2. Clear three-pillar longevity approach
Instead of distributing ingredients across many different supplements, the system focuses on three core mechanisms of healthy ageing:
energy and cellular repair (NAD⁺ support)
antioxidant defence
cellular renewal and autophagy
3. Lower combined monthly cost
Because the three products are bundled together, the complete system can be purchased for around S$150 per month, which may be more affordable than assembling multiple individual supplements to achieve a similar range of benefits.
From Bryan Johnson’s Blueprint to Your Daily Routine
Bryan Johnson’s Blueprint protocol shows how diet, lifestyle habits, and targeted supplements can be used to support long term health and slow aspects of biological ageing. The system combines strict routines, regular health testing, and a wide range of supplements designed to support energy production, reduce oxidative stress, and maintain overall metabolic health. While this approach provides useful insights into how certain nutrients may contribute to healthy ageing, the full Blueprint routine can be complex and expensive for most people to follow.
For Youth highlights a simpler approach to similar goals. Instead of using many different supplements at once, the system focuses on a smaller number of formulas designed to support three key areas: cellular energy, antioxidant protection, and the body’s natural process of clearing damaged components from cells. By using well researched ingredients that are easier for the body to absorb, the aim is to deliver similar benefits while keeping the routine easier to manage day to day.
By focusing on similar longevity mechanisms through fewer, more bioavailable ingredients, simplified protocols such as the Age Defence System's approach aim to make these strategies more practical and accessible. Ultimately, supplements should complement, not replace, the core foundations of healthy ageing: quality sleep, balanced nutrition, regular movement, and meaningful social connection.
Key Takeaways
Longevity fundamentals matter most
The biggest drivers of healthy ageing remain sleep, balanced nutrition, regular exercise, and strong social connections. Supplements can support these foundations but cannot replace them.
Different supplement systems target similar ageing pathways
Both Blueprint and For Youth aim to support cellular energy, antioxidant protection, and metabolic health through targeted nutrients linked to longevity research.
Simplicity and bioavailability can improve practicality
Instead of stacking many separate supplements, formulations that prioritise bioavailable ingredients and coordinated mechanisms may offer a more manageable and cost-efficient daily longevity routine.
Want help choosing the right longevity supplements?
Longevity supplements can be confusing, especially when comparing different stacks and ingredient combinations.
If you have questions about the products mentioned in this article, or want help deciding which supplement routine fits your goals, you can reach out to the For Youth team directly.
We’re happy to help you understand the science, ingredients, and how these supplements may support healthy ageing.
Scientific References
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- Dutta, B. J., Rakshe, P. S., Maurya, N., Chib, S., & Singh, S. (2023). Unlocking the therapeutic potential of natural stilbene: Exploring pterostilbene as a powerful ally against aging and cognitive decline. Ageing Research Reviews, 92. https://doi.org/10.1016/j.arr.2023.102125
- Ahmedy, O. A. (2022). Apigenin attenuates LPS-induced neurotoxicity and cognitive impairment in mice via promoting mitochondrial fusion/mitophagy: role of SIRT3/PINK1/Parkin pathway. Psychopharmacology, 239(12), 3903–3917. https://doi.org/10.1007/s00213-022-06262-x
- Şenol, F. S., Tuğcu-Demiröz, F., Ulutaş, O. K., & Erdoğan, İ. (2025). Phytosomes-unraveling the Unique Properties of Plant-derived Nanotechnological Drug Delivery Systems: A Review. Current Medicinal Chemistry, 32. https://doi.org/10.2174/0109298673319759250116104648
- Dulbecco, P., & Savarino, V. (2013). Therapeutic potential of curcumin in digestive diseases. World Journal of Gastroenterology, 19(48), 9256–9270. https://pmc.ncbi.nlm.nih.gov/articles/PMC3882399/
- Riva, A., Ronchi, M., Petrangolini, G., Bosisio, S., & Allegrini, P. (2019). Improved Oral Absorption of Quercetin from Quercetin Phytosome®, a New Delivery System Based on Food Grade Lecithin. European Journal of Drug Metabolism and Pharmacokinetics, 44(2), 169–177. https://doi.org/10.1007/S13318-018-0517-3
- Gai, S. A. (2025). The beneficial effects of spermidine via autophagy: a systematic review. Theoretical and Natural Science, 73(1), 309–317. https://doi.org/10.54254/2753-8818/2024.19803
- Yan, P., Sun, X., Chen, X., Chen, Y., Wang, X., Su, D., Zhou, H., Gao, L., Lu, L., Wang, J., & Zhang, J. (2018). The Polyphenolic Compound Curcumin Conjugation with an Alkyne Moiety in the Process of Autophagy. The American Journal of Chinese Medicine, 46(3), 673–687. https://doi.org/10.1142/S0192415X18500350
- Liu, W., Hu, M., Cao, F., & Jin, S. (2025). Polyphenols and exercise in autophagy regulation: potential benefits for cancer management and healthspan. Frontiers in Nutrition, 12. https://doi.org/10.3389/fnut.2025.1618813
- Escande, C., Nin, V., Price, N. L., Capellini, V., Gomes, A. P., Barbosa, M. T., O’Neil, L., White, T. A., Sinclair, D. A., & Chini, E. N. (2013). Flavonoid Apigenin Is an Inhibitor of the NAD+ase CD38: Implications for Cellular NAD+ Metabolism, Protein Acetylation, and Treatment of Metabolic Syndrome. Diabetes, 62(4), 1084–1093. https://doi.org/10.2337/DB12-1139
- Suárez-Rivero, J. M., Pastor-Maldonado, C. J., Romero-González, A., Gomez-Fernandez, D., Povea-Cabello, S., Álvarez-Córdoba, M., Villalón-García, I., Talaverón-Rey, M., Suárez-Carrillo, A., Munuera-Cabeza, M., & Sánchez-Alcázar, J. A. (2022). Pterostilbene in Combination With Mitochondrial Cofactors Improve Mitochondrial Function in Cellular Models of Mitochondrial Diseases. Frontiers in Pharmacology, 13. https://doi.org/10.3389/fphar.2022.862085
- Tello‐Palencia, M. A., Yang, T. Y., Sularz, O., Demers, L. E., Ma, Y., Boycott, C., Zhang, H. A., Lubecka, K., Kumar, S., Ramsey, B. S., Torregrosa‐Allen, S., Elzey, B. D., Lanman, N. A., Korthauer, K., & Stefańska, B. (2024). Pterostilbene Targets Hallmarks of Aging in the Gene Expression Landscape in Blood of Healthy Rats. Molecular Nutrition & Food Research. https://doi.org/10.1002/mnfr.202400662
- Huang, H. (2022). A Multicentre, Randomised, Double Blind, Parallel Design, Placebo Controlled Study to Evaluate the Efficacy and Safety of Uthever (NMN Supplement), an Orally Administered Supplementation in Middle Aged and Older Adults. Frontiers in Aging, 3. https://doi.org/10.3389/fragi.2022.851698
- Pompella, A., & Corti, A. (2015). Editorial: the changing faces of glutathione, a cellular protagonist. Frontiers in Pharmacology, 6, 98. https://doi.org/10.3389/FPHAR.2015.00098
- Abnousian, A., Vasquez, J., Sasaninia, K., & Venketaraman, V. (2023). Glutathione Modulates Efficacious Changes in the Immune Response against Tuberculosis. Advances in Cardiovascular Diseases, 11(5), 1340. https://doi.org/10.3390/biomedicines11051340
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- Uchida, Y., Ferdousi, F., Takahashi, S., & Isoda, H. (2024). Comprehensive Transcriptome Profiling of Antioxidant Activities by Glutathione in Human HepG2 Cells. Molecules, 29. https://doi.org/10.3390/molecules29051090
- Champsi, S., & Hood, D. A. (2024). Activation of the Nrf-2 pathway improves the mitochondrial phenotype in skeletal muscle cells. Physiology. https://doi.org/10.1152/physiol.2024.39.s1.410
- Hwang, P. S., Morales Marroquín, F. E., Gann, J. J., Andre, T., McKinley-Barnard, S. K., Kim, C., Morita, M., & Willoughby, D. S. (2018). Eight weeks of resistance training in conjunction with glutathione and L-Citrulline supplementation increases lean mass and has no adverse effects on blood clinical safety markers in resistance-trained males. Journal of the International Society of Sports Nutrition, 15(1), 30. https://doi.org/10.1186/S12970-018-0235-X
- Saito, A., Ishikawa, S., Yang, K., Sawa, A., & Ishizuka, K. (2025). Sulforaphane as a potential therapeutic agent: a comprehensive analysis of clinical trials and mechanistic insights. Journal of Nutritional Science, 14. https://doi.org/10.1017/jns.2025.10033
- Hofer, S. J., Liang, Y., Zimmermann, A., Schroeder, S., Dengjel, J., Kroemer, G., Kroemer, G., Eisenberg, T., Sigrist, S. J., & Madeo, F. (2021). Spermidine-induced hypusination preserves mitochondrial and cognitive function during aging. Autophagy, 17(8), 2037–2039. https://doi.org/10.1080/15548627.2021.1933299
- Bučević Popović, V., Karahmet Farhat, E., Banjari, I., Jelicic Kadic, A., & Puljak, L. (2024). Bioavailability of Oral Curcumin in Systematic Reviews: A Methodological Study. Pharmaceuticals, 17. https://doi.org/10.3390/ph17020164
