The Impact of NMN on Digestive Health

Gut health affects everything — from energy and immunity to mental clarity and ageing. While probiotics get the spotlight, NMN (Nicotinamide Mononucleotide) is quietly emerging as a powerful ally for the gut.

Let’s explore how NMN impacts digestion, nutrient absorption, inflammation, and intestinal barrier function — and how you can benefit from adding it to your longevity stack.

• NMN supports gut barrier integrity , helping prevent harmful bacteria and toxins from entering the bloodstream

• It may promote growth of beneficial gut bacteria , helping rebalance the microbiome

• NMN aids in nutrient absorption and reduces inflammatory load in the digestive system

• Clinical research is still evolving — but early results are highly promising

NMN is a bioactive compound that boosts NAD+ , a molecule vital for energy, metabolism, and cellular repair. In the gut, NAD+ is involved in:

• Supporting energy-hungry gut cells

• Regulating inflammatory responses

• Maintaining the tight junctions that keep the intestinal lining intact

• Powering the growth and function of good gut microbes

This makes NMN uniquely positioned to strengthen digestion from the cellular level up .

Emerging studies show NMN may:

1. Enhance gut barrier function – helping reduce leaky gut and inflammation (2017 study)

2. Improve nutrient absorption – by energising enterocytes in the small intestine (2018)

3. Modulate gut bacteria – with benefits for conditions like IBS (2019)

4. Ease colitis and other inflammatory gut conditions – via mitochondrial repair (2020)

While human trials are still limited, these findings suggest that NMN could play a real role in digestive wellness — especially for those experiencing gut sensitivity or ageing-related decline.

For advanced digestive support, consider The Repair – NMN+ , which includes:

• 450 mg NMN – boosts NAD+ and cellular repair

• 50 mg apigenin – a flavonoid shown to reduce gut inflammation

• 50 mg L-tryptophan – helps modulate mood and serotonin, much of which is produced in the gut

This makes The Repair especially effective for anyone experiencing inflammation , gut-brain issues , or general digestive fatigue .

The Base – NMN contains 250 mg of pure, European-made NMN — great for anyone starting their gut or longevity journey. It’s:

• Enzymatically produced (no solvents)

• Bottled in Singapore

• Third-party tested for purity and heavy metals

Use it as your foundational NAD+ support to improve gut energy, nutrient absorption, and gut lining resilience.

While NMN is generally safe, it’s important to:

• Avoid over-supplementation , which could disrupt NAD+/NADH balance

• Start slow if you have a sensitive stomach

• Watch for rare side effects: nausea, mild fatigue

• Consult a doctor if you have gut-related conditions or take medications

Gut health is foundational — and NMN is proving to be a powerful tool in protecting and optimising digestive function.

• The Base offers pure NAD+ support

• The Repair adds inflammation and mood support

• Together, they help restore balance, reduce inflammation, and fuel a healthier microbiome

Because better digestion doesn’t just start with food — it starts at the cellular level.