
Resveratrol David Sinclair: The Anti-Aging Supplement Backed by Science
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Time to read 2 min
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Time to read 2 min
Do you want to feel — and look — younger? Resveratrol might be the supplement to help you turn back the clock.
Backed by decades of research and championed by Dr. David Sinclair of Harvard Medical School, resveratrol is a powerful antioxidant compound that may activate your longevity genes , improve mitochondrial function, and reduce signs of ageing from within.
Resveratrol is a natural polyphenol found in:
Red grapes
Blueberries
Peanuts
Japanese knotweed
Red wine
It acts as an antioxidant and has been studied for its ability to:
Reduce inflammation
Mimic the effects of calorie restriction
Activate sirtuins , proteins associated with metabolism and lifespan
Support cardiovascular, cognitive, and skin health
Although resveratrol has been consumed in food for centuries, it wasn't until the 1990s that it was identified as a compound of interest.
Then came David Sinclair’s breakthrough in 2003 : his Harvard lab found that resveratrol activated SIRT1 , a longevity-linked gene. This catalysed a wave of research showing potential anti-ageing effects in yeast, mice, and other organisms.
Sinclair later co-founded Sirtris Pharmaceuticals and became one of the world’s best-known voices in the longevity movement.
Resveratrol may support:
💓 Cardiovascular health : improves cholesterol, reduces inflammation, protects arteries
🧠 Brain health : supports memory, learning, and resistance to cognitive decline
🔥 Reduced oxidative stress : neutralises free radicals and protects cells from damage
👵 Slowed cellular ageing : by activating sirtuins and enhancing DNA repair
⚖️ Metabolic balance : may improve insulin sensitivity and blood sugar control
When paired with NAD+ boosters like NMN , these effects may be amplified.
Dr. Sinclair has been open about his supplement routine, which currently includes:
NMN – 1g daily
Resveratrol – 1g daily (taken with olive oil or yoghurt)
Spermidine , Quercetin , Fisetin – in rotation
Occasional metformin
For Youth's products align closely with this stack:
For Youth’s The Grape offers:
💎 99% pure resveratrol
🌿 Derived from Japanese knotweed
🧪 3rd-party tested for safety and purity
💊 250 mg per capsule for flexible dosing
🔬 Supports sirtuin activation, antioxidant defence, and cellular protection
It's one of the cleanest resveratrol options available in Singapore and beyond.
Is resveratrol safe?
Yes, when taken at appropriate doses. Side effects are rare, but it’s best to consult your doctor if you're on medication.
When should I take it?
Take it with a fat-containing meal — e.g. olive oil, yoghurt, or avocado — to improve absorption.
Can it replace a healthy lifestyle?
No. Resveratrol is a tool — not a shortcut. Combine it with healthy eating, movement, and sleep for best results.
Resveratrol isn’t hype — it’s science-backed longevity in a capsule.
With strong research, clinical promise, and public endorsement from leaders like David Sinclair, it stands as one of the most trusted natural tools for ageing well.
If you want antioxidant protection, better energy, and a supplement that works with your biology, The Grape – Resveratrol is the place to start.