Thyroid function isn’t just about hormones – it’s a cornerstone of metabolic health, energy regulation, and cognitive clarity. As longevity science continues to push boundaries, NMN (Nicotinamide Mononucleotide) is emerging as a key player not just in anti-ageing, but potentially in thyroid health regulation as well.

NMN is a direct precursor to NAD+ (Nicotinamide Adenine Dinucleotide), a molecule that fuels our cells and powers everything from energy metabolism to DNA repair. As we age, NAD+ levels drop – taking our energy, resilience, and metabolic efficiency with them. Supplementing with NMN helps replenish NAD+, restoring balance and function across multiple systems.

Current research on NMN and thyroid function is still in early stages, but preliminary insights are worth noting:

• Animal studies using nicotinamide, a close relative of NMN, have shown increased NAD+ levels in thyroid tissue, suggesting possible hormonal interactions.

• One rodent study demonstrated that nicotinamide injection significantly raised thyroid NAD+ levels within hours.

• In humans, studies with nicotinic acid (another vitamin B3 form) indicated lowered thyroid hormone levels without causing hypothyroidism, while a human NMN trial showed no significant changes in TSH or thyroid hormone levels.

• Anecdotal reports have raised questions about a possible link between NMN supplementation and increased TSH levels, though these remain unverified.

While there's potential for a connection between NMN and thyroid activity, more rigorous clinical trials are needed to clarify the mechanisms and long-term implications.

The thyroid doesn’t function in isolation – and neither does NMN. Its benefits extend across the body:

• Bone density support, helping reduce osteoporosis risk
• Joint mobility and inflammatory modulation
• Improved immune resilience and cellular repair
• Metabolic rebalancing and enhanced insulin sensitivity
• Cognitive support and neuroprotection

A 2024 human study by Andrea Maier et al. showed that daily supplementation with even 300 mg of NMN over 8 weeks led to measurable improvements in biomarkers associated with ageing and metabolism – without reported safety concerns. It reinforces the growing consensus: NMN is both effective and well-tolerated.

While the exact pathways are still being mapped, scientists believe NMN – via its NAD+ connection – could:

- Enhance thyroid radiosensitivity by stimulating nitric oxide synthase

- Influence hormone signalling through the generation of organic peroxides

This line of investigation is still evolving but aligns with NMN’s growing profile as a molecule that restores and protects cellular communication.

At For Youth, we challenge the inevitability of ageing. Through advanced formulations, biological age testing, and expert-led insights, we help you understand – and take control of – your healthspan.

We believe longevity should be backed by science, delivered with intention, and accessible to anyone ready to take the first step.

The Repair is our most advanced NMN formulation. Designed for serious health optimisers, it delivers elevated support for NAD+ production, energy metabolism, DNA repair, and overall vitality.

- 450 mg of Uthever® NMN (99% purity) per capsule

- Includes Apigenin and L-Tryptophan to support NAD+ production and cognitive function

- Formulated to energise cells, sharpen focus, and promote healthier ageing

- Premium, high-dose formulation for those serious about longevity

- Take 1 capsule daily in the morning on an empty stomach

- Independently lab-tested in Singapore

- Free from toxins, GMOs, and unnecessary fillers

Built for those who demand results and longevity without compromise.

The Base offers essential NMN support at an accessible price point. It's a clean, simple formulation with 250 mg of Uthever® NMN per capsule.

Perfect for those beginning their NMN journey or maintaining their NAD+ levels without additional enhancements.

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